Synthetic fluorescent organic molecule for the detection of diethylcyanophosphonate via ON-OFF sensing mechanism: paper strips system for real-time application

Imidazo[1,2-a] pyridine-based two probes with different substituents containing oxime and hydroxyl functional groups were synthesised evaluated for detection of tabun nerve agent simulant diethylcyanophosphonate (DCNP). The nucleophile group present on both the can be rapidly phosphorylated by DCNP through a nucleophilic substitution reaction. fluorescent reacting underwent fluorescence OFF, which visualised under UV lamp at 365 nm wavelength. limit 1 2 was calculated as 0.66 μM 0.54 μM, respectively. mechanism studied using spectroscopic techniques revealed that is involved in reaction DCNP. found selective presence other electrophilic interfering agents. Results obtained aqueous media used directly rapid sensitive water without any pretreatment.